Table 2. Associations of diabetes Genetic Risk Score (GRS) with clinical characteristics.
GRS | |||||
---|---|---|---|---|---|
Q1(N = 1588) | Q2(N = 1587) | Q3(N = 1589) | Q4(N = 1582) | P value | |
ER | 0.86 | ||||
Negative | 31.99 | 31.32 | 32.79 | 32.17 | |
Positive | 58.31 | 60.11 | 58.59 | 59.04 | |
Unknown | 9.70 | 8.70 | 8.62 | 8.79 | |
PR | 0.39 | ||||
Negative | 36.27 | 36.48 | 38.89 | 35.46 | |
Positive | 53.78 | 54.95 | 52.24 | 55.31 | |
Unknown | 9.95 | 8.57 | 8.87 | 9.23 | |
TNM | 0.74 | ||||
0-I | 33.69 | 33.96 | 33.86 | 31.54 | |
II | 49.43 | 48.46 | 47.45 | 49.31 | |
III-IV | 9.26 | 9.51 | 10.26 | 10.87 | |
Unknown | 7.62 | 8.07 | 8.43 | 8.28 | |
Diabetes | <0.01 | ||||
No | 85.64 | 83.11 | 81.81 | 76.04 | |
Yes | 6.74 | 7.94 | 9.88 | 14.66 | |
Unknown | 7.62 | 8.95 | 8.31 | 9.29 | |
Age at diagnosis | |||||
53.04(9.87) | 52.61(9.95) | 52.76(9.82) | 52.61(9.97) | 0.60 |
a Percentage for categorical variables (ER/PR/TNM stage), mean (Standard deviation) for the variable of age at diagnosis.
b Pearson’s χ2 test for categorical variables, Kruskal-Wallis test for continuous variable.