TABLE 1.
Group, Brain Region, and Hemisphere |
Brodmann’s Area |
Coordinates |
z Score |
||
---|---|---|---|---|---|
x | y | z | |||
Comparison subjects | |||||
Frontal | |||||
Left | 45,46 | −3 | 34 | 9 | 4.0 |
6 | −38 | 3 | 49 | 3.2 | |
Right | 47 | 27 | 18 | 1 | 3.5 |
Temporal | |||||
Left | 37 | −36 | −60 | −10 | 3.6 |
Right | 20 | 32 | 10 | −31 | 3.5 |
Right occipital | 18 | 32 | −91 | −12 | 4.4 |
Right cerebellum | — | 41 | −52 | −21 | 4.1 |
Patients | |||||
Frontal | |||||
Left | 10 | −36 | 53 | 17 | 3.5 |
Right | 10 | 29 | 53 | 2 | 3.2 |
Left temporal | 38 | −13 | 12 | −35 | 4.5 |
Right thalamus | — | 6 | −13 | 13 | 3.1 |
Left cerebellum | — | −1 | −56 | −31 | 2.8 |
Comparison subjects minus patients | |||||
Frontal | |||||
Left | 45 | −40 | 32 | 5 | 3.1 |
8,9 | −27 | 37 | 37 | 4.1 | |
Left temporal | 38 | −47 | 20 | −17 | 3.2 |
Nonmedicated minus medicated patients | |||||
Left frontal | 4 | −52 | −7 | 13 | 3.4 |
Left cerebellum | — | −47 | −52 | −21 | 3.4 |
Value during word encoding minus value during baseline.
Estimated Brodmann’s areas and coordinates from Talairach and Tournoux (59); z scores represent peak activation in the cluster.