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. 2015 Feb 13;10(2):e0116803. doi: 10.1371/journal.pone.0116803

Table 3. Univariate analysis for disease-free survival and overall survival.

Parameter DFS OS
HR 95% CI P HR 95% CI P
Age (years) 0.153 0.029
    <60 1 1
    ≥60 1.31 0.89–1.94 1.58 1.03–2.42
Gender 0.724 0.604
    Male 1 1
    Female 0.94 0.64–1.37 0.61 0.59–1.36
Tumor sites 0.732 0.580
    Head 1 1
    Body/tail 1.07 0.72–1.59 1.13 0.73–1.76
Tumor size 0.595 0.150
    T1–2 1 1
    T3–4 1.11 0.76–1.62 1.35 0.89–2.05
Lymph node metastasis 0.020 0.006
    No 1 1
    Yes 1.55 1.05–2.28 1.77 1.16–2.71
TNM stage <0.001 <0.001
    I-II 1 1
    III 4.29 2.28–8.10 3.32 1.73–6.37
Resection margins 0.022 <0.001
    Negative 1 1
    Positive 1.64 1.05–2.56 2.24 1.28–3.89
Tumor differentiation 0.000 <0.001
    Well/moderate 1 1
    Poor 2.07 1.38–3.09 2.41 1.57–3.69
EGFR expression 0.493 0.161
    Low 1 1
    High 1.14 0.78–1.66 1.34 0.88–2.03
CXCR4 expression 0.003 <0.001
    Low 1 1
    High 1.78 1.20–2.64 2.41 1.54–3.76
EGFR/CXCR4 coexpression <0.001 0.001 <0.001
    Negative 1 1
    Positive 2.35 1.51–3.67 3.16 1.96–5.09