Figure 7.

ROI analysis of the inferior olive (IO). a, Before considering heart rate, the right inferior olive showed a general decrease in activation compared with rest, although this was not significant. b, Following the inclusion of heart rate covariates into the model, neither the right nor the left olive showed a significant change in heart rate from rest in any of the four conditions. c, Effect of different physiological variables on the BOLD signal in the inferior olive. Left, Nearly 25% of the variance of the BOLD signal could be explained by the cardiac or respiratory phase (Glover et al., 2000), consistent with the proximity of the inferior olive to the arterial blood supply. Right, Heart rate alone accounted for ∼2% of the variance in the BOLD signal in the olive.