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. Author manuscript; available in PMC: 2015 Feb 19.
Published in final edited form as: Patient. 2014;7(4):427–436. doi: 10.1007/s40271-014-0066-z

Table 2.

Multinomial model without imputation of missing variables, comparing men who remain in the active surveillance program, men who left the program on a clinician's recommendation, and men who self-elected to leave the program. Men with missing variables are excluded from the regression modela,b

RRR (95 % CI)c

Left on physician's recommendation Self-elected to leave
Age at diagnosis
 40 to <60 years 1 (reference) 1 (reference)
 60 to <70 years 0.97 (0.60–1.57) 0.55 (0.30–1.02)
 ≥70 years 1.08 (0.63–1.85) 0.16 (0.06–0.43)
PSA level at diagnosis
 <4 ng/mL 1 (reference) 1 (reference)
 4 to <10 ng/mL 1.71 (1.17–2.48) 1.95 (1.09–3.50)
 ≥10 ng/mL 0.80 (0.38–1.66) 0.74 (0.21–2.65)
Race/ethnicity
 White 1 (reference) 1 (reference)
 Black 1.24 (0.64–2.42) 0.67 (0.19–2.37)
 Other 1.28 (0.50–3.27) 0.43 (0.05–3.42)
Family history of prostate cancer
 No 1 (reference) 1 (reference)
 Yes 1.10 (0.75–1.62) 1.24 (0.69–2.21)
Family history of any cancer
 No 1 (reference) 1 (reference)
 Yes 1.17 (0.83–1.65) 1.26 (0.74–2.15)
Education
 Less than college 1 (reference) 1 (reference)
 Bachelor's degree 1.06 (0.65–1.73) 0.55 (0.26–1.14)
 Graduate degree 0.82 (0.52–1.29) 0.64 (0.34–1.21)
Marital status
 Not married 1 (reference) 1 (reference)
 Married or partnered 0.86 (0.53–1.38) 0.40 (0.15–1.03)

CI confidence interval, RRR relative risk ratio

a

Excludes patients who withdrew from the program without being treated (n = 31), are no longer in the Johns Hopkins program but are being followed elsewhere (n = 69), were lost to follow-up (n = 15), or are deceased (n = 46)

b

In the multinomial model, the reference category is men who remain in the active surveillance program. The models simultaneously adjust for all covariates listed in the table. Only completely ascertained cases are included in the regression model

c

Bold text indicates significance at the p < 0.05 level