TABLE 2.

Local Cluster-Level Maxima of Blood-Oxygen-Level-Dependent fMRI Signal Change During Correct Deep Minus Shallow Word Encoding in Healthy Comparison Subjects and Patients With Schizophrenia^a

Group and Region	Estimated Brodmann’s Area	z Scoreb	Coordinatesc
			x	y	z
Comparison subjects (N=14)
Left inferior frontal gyrus	47	3.99	−40	30	−12
Left superior frontal gyrus	10	2.90	−20	46	0
Left insula	13	3.09	−40	14	16
Patients (N=14)
Left inferior frontal gyrus	44	3.96	−44	10	28
Left parahippocampal gyrus	36	4.11	−36	−34	−12
Left superior temporal gyrus	22	2.85	−52	−54	16
Right caudate gyrus		3.77	20	−38	16
Right cerebellum		2.99	4	−62	−24
Patients > comparison subjects
Left thalamus		3.78	−8	−30	4
Left hippocampus		3.37	−32	−42	−4
Left lingual gyrus	19	3.34	−32	−58	−4

^aValues were calculated during word encoding for correctly classified words.

^bPeak activation in a cluster of at least eight voxels in which the difference in signal change exceeded an extent- and threshold-corrected p value of 0.05.

^cCoordinates from the stereotaxic atlas of Talairach and Tournoux (29).