Table 1.
Kidney transplantation (KT) recipients, stratified by frailty status at the time of transplantation (n = 537)
| Nonfrail (n = 253) | Intermediately frail (n = 177) | Frail (n = 107) | p-Value | |
|---|---|---|---|---|
| Recipient | ||||
| Age | 50.7 (14.0) | 54.5 (13.7) | 55.8 (14.0) | 0.002 |
| African American race | 37.6 | 39.6 | 41.1 | 0.8 |
| Female sex | 39.9 | 40.7 | 39.3 | 0.9 |
| BMI (kg/m2) | 27.3 (6.0) | 27.6 (5.7) | 27.6 (5.9) | 0.9 |
| Diabetes | 13.8 | 22.0 | 20.6 | 0.1 |
| Time on dialysis (years) | 2.0 (0.4–4.4) | 2.0 (0.5–3.8) | 1.7 (0.4–3.7) | 0.5 |
| HCV positive | 8.3 | 7.9 | 12.2 | 0.4 |
| Previous transplant | 18.2 | 13.0 | 17.8 | 0.3 |
| Transplant | ||||
| PRA = 0 | 38.3 | 36.2 | 59.8 | 0.8 |
| 0 HLA mismatch | 4.0 | 5.7 | 3.7 | 0.7 |
| Preemptive KT | 21.3 | 13.6 | 17.8 | 0.1 |
| Cold ischemia time | 9.7 (1.7–24.0) | 12.8 (1.6–28.6) | 10.5 (2.1–26.4) | 0.5 |
| Donor | ||||
| Live donor | 48.2 | 42.8 | 42.1 | 0.3 |
| ECD | 4.0 | 4.0 | 12.2 | 0.01 |
| DCD | 7.5 | 9.6 | 8.4 | 0.7 |
| White race | 73.9 | 71.2 | 74.8 | 0.8 |
| History of hypertension | 14.2 | 15.3 | 20.6 | 0.3 |
| Creatinine > 1.5 | 15.8 | 17.0 | 12.2 | 0.6 |
Nonfrail was defined as a score of 0 or 1, intermediately frail was defined as a score of 2 and frail was defined as a score of 3 or higher. The mean [SD] are presented for age and BMI. The median and interquartile range are presented for time on dialysis and cold ischemia time. All other measures are %. HCV, hepatitis C virus; PRA, panel reactive antibody; ECD, deceased expanded criteria; DCD, donation after cardiac death donor.