Table 3.

Risk of mortality in kidney transplantation (KT) recipients, by frailty status at the time of transplantation (n = 537)

	Hazard ratio (95% confidence interval) for mortality
	Unadjusted	Adjusted (hybrid)	Adjusted (traditional
Intermediately frail	1.70 (0.82–3.52)	1.49 (0.73–3.06)	1.44 (0.69–3.02)
p-Value	0.153	0.276	0.332
Frail	2.58 (1.21–5.49)	2.17 (1.01–4.65)	2.22 (1.03–4.81)
p-Value	0.014	0.047	0.042

Nonfrail was defined as a score of 0 or 1, intermediately frail was defined as a score of 2 and frail was defined as a score of 3 or higher. The adjusted model was adjusted for recipient age, sex, race, diabetes, time on dialysis and preemptive KT, as well as donor type (deceased standard criteria donor, deceased expanded criteria, donation after cardiac death donor vs. live) and cold ischemia time. In the hybrid approach, we constrained the coefficients for all the adjustment factors to be the coefficients as estimated from the Scientific Registry of Transplant Recipients. In the traditional approach, a forced model was fit to only our single-center data.