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. Author manuscript; available in PMC: 2015 Feb 19.
Published in final edited form as: Pain Med. 2014 Sep 19;16(2):249–256. doi: 10.1111/pme.12545

Figure 2.

Figure 2

(A) Neuro-hormones only: Component 1 top loadings: IL1a, IL8, AgRP; Component 2 top loadings: cortisol, MCP1, DynA. Green = pain, red = no pain. Ellipses are 95% confidence intervals. (B) Metabolites only: Component 1 top loadings: valine, proline, hypoxanthine; Component 2 top loadings: propionate, formate, acetate. Green = pain, red = no pain. Ellipses are 95% confidence intervals. (C) Metabolites + neuro-hormones: metabolites (Component 1 loadings: valine, proline, hypoxanthine), hormones/peptides (Component 2 top loadings: cortisol, MCP1, prolactin). Green = pain, red = no pain. Ellipses are 95% confidence intervals. AgRP = agouti-related peptide; DynA = dynorphin A; IL = interleukin; MCP1 = monocyte chemotactic protein-1.