Table 2.
Comparison of cardiac and pulmonary investigation parameters in pulmonary arterial hypertension and non-pulmonary hypertension groups
| Investigations | PAH | Non-PH | P value |
|---|---|---|---|
| (n = 27) | (n = 34) | ||
| Mean ± SD or n (%) | Mean ± SD or n (%) | ||
| TTE parameters | |||
| RA area, cm 2 | 20.8 ± 6.6 | 17.6 ± 4.2 | 0.038 |
| TRV, m/s | 3.4 ± 0.6 | 2.7 ± 0.9 | 0.0002 |
| sPAP, mm Hg | 57.7 ± 19.6 | 41.6 ± 10.6 | 0.0004 |
| RAD a on ECG | 3 (13) | 3 (12) | 0.073 |
| PFT results | |||
| FVC, % pred | 91.6 ± 15.1 | 90.9 ± 25.6 | 0.900 |
| DLCO b , % pred | 47.9 ± 11.7 | 60.6 ± 14.9 | 0.0008 |
| FVC/DLCO | 2.0 ± 0.5 | 1.6 ± 0.4 | 0.0003 |
| RHC results | |||
| mPAP, mm Hg | 36.4 ± 10.1 | 19.4 ± 3.4 | <0.0001 |
| mRAP, mm Hg | 9.7 ± 3.9 | 5.5 ± 2.9 | 0.0001 |
| PVR, Wood units | 5.7 ± 3.3 | 1.9 ± 0.9 | <0.0001 |
aRight axis deviation (RAD) defined as QRS axis of at least 90°. bDiffusing capacity for carbon monoxide (DLCO) values are reported as percentage predicted values, corrected for hemoglobin. ECG, electrocardiogram; FVC, forced vital capacity (percentage predicted); mPAP, mean pulmonary artery pressure; mRAP, mean right atrial pressure; PAH, pulmonary arterial hypertension; PFT, pulmonary function test; PH, pulmonary hypertension; pred, predictive value; PVR, pulmonary vascular resistance; RA, right atrium; RHC, right heart catheterization; SD, standard deviation; sPAP, systolic pulmonary artery; TRV, tricuspid regurgitant velocity; TTE, transthoracic echocardiography.