Table1.
HC (N = 24) | FESZ (N = 18) | Statistic | |||
---|---|---|---|---|---|
t or χ2 | df | P | |||
Female sex, N (%) | 11 (45.8) | 5 (27.8) | 1.42 | 1 | .23 |
Age at baseline | 20.0 (3.85) | 21.7 (4.55) | 3.85 | 40 | .18 |
Age at follow-up | 21.0 (3.87) | 22.8 (4.54) | 3.87 | 40 | .17 |
Inter-EEG interval (mo) | 12.7 (4.03) | 11.7 (3.33) | 4.03 | 40 | .38 |
Handednessa | 0.7 (2.46) | 1.9 (3.25) | 2.46 | 40 | .17 |
Education years | 13.4 (2.67) | 14.1 (2.69) | 2.67 | 40 | .45 |
Parental SESb | 1.7 (0.91) | 2.2 (1.17) | 0.91 | 40 | .12 |
Current IQc | 117.9 (23.66) | 105.5 (14.54) | 23.66 | 39 | .06 |
Premorbid IQd | 118.4 (15.58) | 111.2 (16.41) | 15.58 | 40 | .15 |
GAF | |||||
Baseline | 84.1 (6.94) | 49.4 (13.40) | 10.91 | 40 | <.001* |
Follow-up | 82.5 (9.51) | 62.1 (15.52) | 5.19 | 39 | <.001* |
BPRS Total Score | |||||
Baseline | 44.0 (13.7) | ||||
Follow-up | 35.8 (10.6) | ||||
BPRS Positive Symptom Score | |||||
Baseline | 9.2 (3.9) | ||||
Follow-up | 7.0 (2.5) | ||||
BPRS Negative Symptom Score | |||||
Baseline | 11.8 (5.2) | ||||
Follow-up | 9.4 (2.6) | ||||
Spatial Span subtest of the Wechsler Memory scale | |||||
Baseline | 20.3 (3.6) | 16.9 (2.9) | 3.2 | 39 | .003** |
Follow-up | 19.8 (3.1) | 16.4 (3.7) | 3.2 | 39 | .003** |
Medication (CPZ equivalents) | |||||
Baseline | 267.9 (206.8) | ||||
Follow-up | 300.0 (300.4) |
Note: Values are means (SDs) unless otherwise indicated. SES, socioeconomic status; CPZ, chlorpromazine.
aBased on the Annett Handedness Scale total score.
bBased on the Hollingshead method. Higher scores indicate lower socioeconomic status.
cEstimated from Vocab and Block Design T-scores of Wechsler Abbreviated Scale of Intelligence.
dEstimated from Reading scale of Wide Range Achievement Test.
*Patients with first-episode schizophrenia showed significantly lower Global Assessment of Functioning scale scores compared with healthy comparison subjects both at baseline and follow-up.
**Patients with first-episode schizophrenia showed significantly lower Spatial Span scores compared with healthy comparison subjects both at baseline and follow-up.