Table 3.

Multivariate analysis of factors predicting disease-free survival in adjuvant chemotherapy with platinum-based agent

	Univariate			Multivariate
	HR	95%CI	P value	HR	95%CI	P value
P value
Gender
Male/female	1.25	0.49-3.18	0.639	2.11	0.77-5.82	0.149
Histology
non-SQ/SQ	1.89	0.56-6.37	0.303	2.38	0.65-8.74	0.191
Pathological T factor
T3-4/T1-2	1.81	0.79-4.13	0.160	1.89	0.70-5.11	0.208
Pathological N factor
Positive/negative	3.63	1.34-9.85	0.011	3.15	1.12-8.85	0.030
Pleural invasion
p1-3/p0	1.13	0.77-1.67	0.533	0.82	0.50-1.36	0.453
Vascular invasion
Positive/negative	2.25	0.93-5.52	0.072	3.79	1.26-11.35	0.017
Cox-2 expression
Positive/negative	3.14	1.16-8.49	0.024	3.96	1.38-11.38	0.011

P value was calculated by log-rank test. HR: hazard ratio; 95%CI: 95% confidence interval; SQ: squamous cell carcinoma; Cox-2: cyclooxygenase-2.