Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jan 27;8:1. doi: 10.1186/s13045-014-0099-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Hu et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

hBM-MSC-induced β-catenin stabilization is essential for the drug resistance of ALCs, and is eliminated by gal-3 knockdown. (A) The transcriptional level of β-catenin in all four cell lines cultured alone or with hBM-MSCs. (B) The expression of β-catenin and gal-3 in ALCs after transfection with gal-3 shRNA or vector, cultured alone or with hBM-MSCs. (C) ALCs, cultured alone or with hBM-MSCs, were pretreated with ICG-001 (5 μM for Reh cells, 10 μM for Jurkat and Kasumi-1) for 30 minutes, then IDA at indicated concentration was added. Apoptosis was measured after exposure to IDA for 48 h.