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. 2015 Feb 2;2015:390812. doi: 10.1155/2015/390812

Figure 4.

Figure 4

(a) MDR1 and MRP gene expression in SGC7901 and SGC7901/VCR cells. *** P < 0.01 versus control. (b) YJHD suppressed the mRNA expression of chemotherapeutic agent resistance-related genes in SGC7901/VCR cells. Fold changes: relative gene expression after treatment with YJHD at 0.5 mg/mL for 48 h compared to control. * P < 0.05 compared with control. (c) Western blot analysis of STMN1, TS, TUBB3, MRP, and P-gp in control cells and cells treated with YJHD at 0.5 mg/mL, 1 mg/mL, and 2 mg/mL. (d) Bar graph of the densitometric values of the bands corresponding to MRP, P-gp, STMN1, TS, and TUBB3 normalized relative to β-actin. * P < 0.05 versus control, ** P < 0.01 versus control.