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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Neurosurgery. 2015 Mar;76(3):291–301. doi: 10.1227/NEU.0000000000000624

Table 3.

Symptomatic Hemorrhages Within 30 Days of EVD Insertion Among 250 Cases Enrolled in CLEAR III

Patient # Bleed Timing Anticoagulation
1 Catheter track (during dosing) 5hrs. (after 3 doses) No prophylactic anticoagulation
2 Catheter track (during dosing) 31hrs. (after 2 doses) No prophylactic anticoagulation
3 Catheter track (during dosing) 48hrs DVT prophylaxis (SQ Heparin)
4 New catheter placed for hydrocephalus after protocol; New ICH (new pontine hemorrhage) Day 16 Full anti-coagulation (site entered reason as ‘prevention of thrombosis’
5 New catheter placed for hydrocephalus after protocol; (new massive IVH in left lateral ventricle) Day 22 On Enoxaparin (DVT prophylaxis)
6 Spontaneous new bleed; New ICH (different location than original stroke) Day 16 On Enoxaparin (DVT prophylaxis)