Table 1.
Characteristics of the Analytic Cohort of 888 Men Ages 65 Years and Older by 25(OH)D Quartile
| Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | P-value | |
|---|---|---|---|---|---|
| Total 25(OH)D (ng/ml; mean ± SD) | 15.1 ± 3.7 | 22.3 ± 1.6 | 27.0 ± 1.4 | 34.8 ± 5.2 | |
| Total 25(OH)D (ng/ml, range) | (11.4-18.8) | (20.7-23.9) | (25.6-28.4) | (29.6-40) | |
| Baseline Characteristics | |||||
| Number (% cohort) | 221 | 219 | 226 | 222 | |
| Age (years; mean ± SD) | 74.5 ± 6.2 | 73.6 ± 6.0 | 73.85 ±5.8 | 72.99 ± 5.4 | 0.06 |
| Race | |||||
| Caucasian (n, %) | 188 (85) | 203 (93) | 206 (91) | 209 (94) | |
| Other (n, %) | 33 (15) | 16 (7) | 20 (9) | 13 (6) | 0.006 |
| BM (kg/m2) | 28.32 ± 4.04 | 27.41 ± 3.61 | 27.23 ± 3.47 | 26.70 ± 3.28 | <0.001 |
| Height | |||||
| Current Height in cm ( mean ± SD) | 173.14 ± 7.24 | 174.45 ± 6.94 | 173.6 ± 6.80 | 174.96 ± 6.46 | 0.02 |
| Weight | |||||
| Current Weight in kg ( mean ± SD) | 85.04 ± 13.96 | 83.71 ± 13.77 | 82.16 ± 12.09 | 81.82 ± 11.63 | 0.03 |
| Smoking status | |||||
| Current smokers (n, %) | 10 (5) | 10 (5) | 8 (4) | 2 (1) | |
| Past smokers (n, %) | 138 (62) | 127 (58) | 130 (58) | 141 (64) | |
| Never smoked (n, %) | 73 (33) | 82 (37) | 88 (39) | 79 (36) | |
| Total Pack years (mean ± SD) | 32.78 ± 27.69 | 30.15 ± 28.15 | 30.06 ± 24.85 | 29.54 ± 25.90 | 0.23 |
| Alcohol Consumption (drinks/week in the last year) | |||||
| none (n, %) | 77 (35) | 75 (34)** | 75 (33) | 61 (27) | |
| 1-<7drinks (n, %) | 80 (36) | 84 (39)** | 96 (42) | 82 (37) | |
| 7 or more (n, %) | 64 (29) | 59 (27)** | 55 (24) | 79 (36) | 0.17 |
| Physical Activity (PASE score; mean ± SD) | 134.65 ± 75.21 | 146.90 ± 65.36 | 147.32 ± 63.97 | 157.65 ± 67.44 | 0.01 |
| Reported Health Status for Age | |||||
| Good/Excellent (n, %) | 175 (79) | 190 (87) | 195 (86) | 205 (92) | |
| Very Poor/Poor/Fair (n, %) | 46 (21) | 29 (13) | 31 (14) | 17 (8) | 0.001 |
| Non-trauma Fracture since age 50 (n,%) | 43 (19) | 39 (18) | 31 (14) | 43 (19) | 0.34 |
| Inability to rise ≥ 1 time unassisted from a chair (n, %) | 4 (2) | 3 (1) | 2 (1) | 3 (1) | 0.81 b |
| Diagnosis of Osteoporosis (n, %) | 9 (4) | 8 (4) | 11 (5) | 11 (5) | 0.9 b |
| Diagnosis of Arthritis (n, %) | 102 (46) | 103 (47) | 103 (46) | 105 (47) | 0.98 |
| Ever used osteoporosis medication (n, %) | 3 (1) | 8 (4) | 8 (4) | 10 (5) | 0.25 b |
| Season of Baseline visita | |||||
| Winter (Jan-Mar; n, %) | 58 (26) | 46 (21) | 39 (17) | 20 (9) | |
| Spring (Apr-June; n, %) | 87 (39) | 82 (37) | 76 (34) | 69 (31) | |
| Summer (Jul-Sept; n, %) | 32 (14) | 49 (22) | 64 (28) | 93 (42) | |
| Fall (Oct-Dec; n, %) | 44 (20) | 42 (19) | 47 (21) | 40 (18) | <0.001 |
| Latitude of Clinic Site (n, %)a | |||||
| High (Minneapolis 44°, Pittsburgh 40° and Portland 45°; n, %) | 149 (67) | 116 (53) | 113 (50) | 96 (43) | |
| Low (Birmingham 33°, Palo Alto 37°, and San Diego 32°; n, %) | 72 (33) | 103 (47) | 113 (50) | 126 (57) | <0.001 |
a
Latitudes and seasons as previously described [2]
b
Fisher's exact method used
**
One participant refused to answer