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. 2014 Dec 22;100(3):E387–E395. doi: 10.1210/jc.2014-3630

Figure 2.

Figure 2.

Morphometric analyses of islets in 12-LO+ and 12-LO− cases. Islet area, β-cell area, and 12-LO+ area were determined as in Materials and Methods in 12-LO+ and 12-LO− cases from nondiabetic (non-DM), AAb+, T1D, and T2D subjects. 12-LO expression was not seen in any nondiabetic donors. Data are means ± SEM (n = 3–4). A and B, islet area (A) and β-cell area (B) were compared using 2 statistics: a, one-way ANOVA with Dunnett posttest in comparison with nondiabetic, ***, P < .001; b, Student t tests between 12-LO+ and 12-LO− donors of each diabetic status, #, P < .05. C–E, 12-LO+ areas were expressed in relation to pancreatic area (C), islet area (D), and β-cell area (E) in 12-LO+ subjects. A Student t test was use for comparison between the indicated groups: *, P < .05; **, P < .01.