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. 2014 Dec 22;100(3):E387–E395. doi: 10.1210/jc.2014-3630

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Figure 5. — Quantification of PP intensity in islets from 12-LO⁺ and 12-LO⁻ donors. The intensity of PP immunostaining within islets was quantified as in Materials and Methods in the uncinate (A) and nonuncinate (B) regions of the pancreas. Donors with AAb⁺, T1D, and T2D were separated based on the positivity of 12-LO in islets. We did not identify subjects with 12-LO⁺ cells in nondiabetic (non-DM) donors. Values are expressed as taking the average intensity of PP staining in the uncinate region of nondiabetic donors as 1. Data are means ± SEM (n = 3–4). Two statistical comparisons were performed: a, one-way ANOVA with Dunnett posttest in comparison with nondiabetic, *, P < .05; ***, P < .001; b, Student t tests between 12-LO⁺ and 12-LO⁻ donors of each diabetic status, #, P < .05; ##, P < .001; ####, P < .0001.