Table 3.
Variables Predicting Cancer-Related Worry in Thyroid Cancer Survivors
| Variable | Univariate Analyses, Mean Difference ASC Total Score (Student's t Test)a | Multivariable Linear Regression Model (n = 764 for Model)b |
|---|---|---|
| Age <50 y | 1.41 (0.81, 2.00); P < .001 | 1.65 (0.96, 2.27); P < .001 |
| Married/common-law marital status (compared to single, divorced, separated, or widowed) | 0.83 (0.13, 1.54); P = .020 | 0.96 (0.15, 1.77); P = .021 |
| Have children (compared to no children) | 0.82 (0.13, 1.50); P = .019 | 0.85 (0.09, 1.61); P = .029 |
| Birth country outside Canada (vs Canada) | 0.59 (−0.20, 1.38); P = .145 | 0.16 (−0.68, 1.00); P = .705 |
| Short-term cancer survivor (≤5 y after diagnosis vs >5 y) | 0.75 (0.14, 1.36); P = .016 | 0.81 (0.15, 1.47); P = .017 |
| Any history of distant metastases | 1.51 (−0.06, 3.08); P = .059 | 1.47 (−0.09, 3.04); P = .065 |
| Current suspected or proven recurrent or persistent disease | 2.03 (1.26, 2.80); P < .001 | 1.77 (0.99, 2.54); P < .001 |
| College education or higher (vs lower) | 0.34 (−0.37, 1.05); P = .352 | — |
| History of any RAI treatment for thyroid cancer | 0.21 (−0.64, 1.06); P = .631 | — |
Data are expressed as estimate of coefficient of mean difference (95% CI); P value; dashes, not applicable.
a
Unequal variances were assumed between groups.
b
All variables for which P ≤ .2 in the univariate analyses were included in the multivariable model. The final model r value is 0.288, and R-squared is 0.083. The variance inflation factor for each factor in the multivariable model was estimated as follows: age, 1.07; marital status, 1.16; having children, 1.17; birth country, 1.02; duration of survivorship, 1.03; any history of distant metastases, 1.09; and current thyroid cancer status, 1.08.