Table 1.
Demographics of children with congenital hemolytic anemia undergoing total splenectomy or partial splenectomy
| Overall | Hereditary spherocytosis |
Sickle cell disease |
Other | p-value | |
|---|---|---|---|---|---|
| N | 100 | 40 (40%) | 50 (50%) | 10 (10%) | |
| Demographics | |||||
| Gender | 0.453 | ||||
| Male | 49 (49%) | 19 (47.5%) | 27 (54%) | 3 (30%) | |
| Female | 51 (51%) | 21 (52.5%) | 23 (46%) | 7 (70%) | |
| Race/Ethnicity | <0.001 | ||||
| White | 35 (35%) | 30 (75%) | 0 (0%) | 5 (50%) | |
| Black | 53 (53%) | 6 (15%) | 46 (92%) | 1 (10%) | |
| Hispanic | 7 (7%) | 3 (7.5%) | 4 (8%) | 0 (0%) | |
| Other | 5 (5%) | 1 (2.5%) | 0 (0%) | 4 (40%) | |
| Preoperative Vaccinations | |||||
| Pneumovax | 0.001 | ||||
| Yes/No or unknown | 87/13 (87%) | 34/6 (85%) | 48/2 (96%) | 5/5 (50%) | |
| Meningovax or Menactra | 0.001 | ||||
| Yes/No or unknown | 80/20 (80%) | 30/10 (75%) | 46/4 (92%) | 4/6 (40%) | |
| Postoperative Antibiotics | 0.348 | ||||
| Yes/No or unknown | 98/1 (99%) | 38/1 (97%) | 50/0 (100%) | 10/0 (100%) |
Numbers represent counts (%) for each variable in the overall cohort and grouped by diagnosis. P-values represent Pearson’s Chi-square or Fisher’s exact test as appropriate for a difference between the diagnostic groups.