Table 1.
RBC (×106/µL) |
HGB (g/dL) |
HCT (%) |
MCV (fL) |
MCH (pg) |
MCHC (g/dL) |
CH (pg) |
RDW (%) |
Retics (%) |
Abs Retics (×106/µL) |
|
---|---|---|---|---|---|---|---|---|---|---|
Wild Type | 9.5 ± 0.6 | 13.9 ± 0.6 | 43.3 ± 6.0 | 45.2 ± 3.6 | 14.5 ± 0.3 | 32.3 ± 3.1 | 13.9 ± 0.4 | 13.8 ± 0.8 | 2.6 ± 1.0 | 0.3 ± 0.1 |
TSAP6 KO | 15.9 ± 1.2*** | 9.2 ± 0.9*** | 34.3 ± 6.4* | 21.5 ± 3.2*** | 5.8 ± 0.3*** | 27.2 ± 2.8** | 5.7 ± 0.2*** | 27.2 ± 2.2*** | 5.7 ± 3.0* | 0.9 ± 0.4* |
Data presented X ± SD, n=6 in each group.
P ≤ 0.05 vs wild type;
P ≤ 0.01 vs wild type;
P ≤ 0.001 vs wild type.
All animals were at least 4 months of age.
RBC: Red Blood Cells; HGB: hemoglobin; HCT: Hematocrit; MCV: Mean Corpuscular Volume; MCH: Mean Corpuscular Hemoglobin; MCHC: Mean Cell Hemoglobin Concentration; CH: Corpuscular Hemoglobin; RDW: Red cell Distribution Width; Retics: Reticulocyte count; Abs Retic: Absolute Reticulocyte Count.