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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: J Immunol. 2015 Jan 1;194(1):210–222. doi: 10.4049/jimmunol.1402453

FIGURE 8.

FIGURE 8

β-catenin stabilization promotes activation of antigen-specific CD8+ T cells during viral infection. (A–C) Quantification of gB-8p-specific CD8+ T cells in Ex3fl/fl and Ex3DC−/− spleens 6 days post-VACV-gB infection. (A) Representative plots of MHCI-restricted gB-8p:Kb tetramer-positive CD8+ T cells, and (B) percentage and (C) total number of gB-8p:Kb+CD8+ T cells. (D–F) IFN-γ production by gB-8p-specific CD8+ T cells in Ex3fl/fl and Ex3DC−/− spleens 6 days post-VACV-gB infection. (D) Representative plots of CD8+CD44+IFN-γ+ T cells following gb-8p restimulation of splenocytes, and (E) percentage and (F) total number of gB-8p-specific CD8+CD44+IFN-γ+ T cells. The data shown are the combination of 2 independent experiments (n=9–13). **, p<0.01.