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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Psychosom Med. 2015 Feb-Mar;77(2):167–175. doi: 10.1097/PSY.0000000000000143

Figure 1. Percent of Participants Reporting Clinically Significant Improvement in Hot Flashes From Baseline by Intervention Arm.

Figure 1

Data points are the percent improved at each time point in the placebo group (N=247) and in the active drug group (N=297). Not all participants had data at all weeks.

Repeated measures logistic regression modeled 50% reduction in HF from baseline (yes/no) as a function of intervention (active drug vs. placebo), week (1-8) as a continuous variable and intervention*week, adjusted for study and clinic center.

Main effects of intervention and week, P<0.001 for each; interaction between intervention and week, P=0.88.