Table 1.

Baseline Characteristics by Intervention Arm

Variable	Combined Active N=297		Combined Placebo N=247		p-value1
	n	%	N	%
Age, mean (SD)	54.4 (4.1)		54.3 (3.8)		0.88
Ethnicity					0.86
White	166	55.9	139	56.3
African American	117	39.4	94	38.1
Other / Unknown	14	4.7	14	5.7
Menopause Status					0.86
Menopause transition	53	17.8	40	16.2
Postmenopause	216	72.7	182	73.7
Indeterminate2	28	9.4	25	10.1
Years of hot flashes, mean (SD)	6.5 (6.0)		6.3 (5.5)		0.66
PHQ-9 Depression >=5	83	27.9	61	24.7	0.39
SCL Anxiety > 0.3	70	23.6	66	26.7	0.65
BMI, mean (SD)	28.8 (6.6)		28.4 (6.7)		0.58
≥ 30 kg/m2 (n, %)	102	34.3	83	33.6	0.95
≤ High school / GED	46	15.5	47	19.0	0.30
Full-time employment	140	47.1	115	46.6	0.55
≥ 1 alcoholic drink / day	46	15.5	44	17.8	0.28
Current smoker	52	17.5	50	20.2	0.71
Screening HF Variables
Average HF / Day, mean (SD)	8.9 (5.9)		8.5 (5.0)		0.38
HF Frequency SD, mean (SD)	2.0 (1.3)		1.9 (1.1)		0.50
Average HF severity, mean (SD)	2.1 (0.5)		2.1 (0.5)		0.89
Average HF bother, mean (SD)	3.1 (0.5)		3.1 (0.5)		0.96

¹p-values from t-tests for continuous and chi-square tests for categorical characteristics

²Menses indeterminate, met hormone or other criteria