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. 2015 Feb 18;10(2):e0115977. doi: 10.1371/journal.pone.0115977

Table 1. Blood glucose and brachial artery flow-mediated dilation parameters during session 1 and 2, and intra-class correlations.

Parameter Session 1 Session 2 ICC
t = - 40 t = - 15 / t = 0 t = 30 t = 60 t = 75 t = 120 t = - 40 t = -15 / t = 0 t = 30 t = 60 t = 75 t = 120 Intra- session Inter-session
Glucose, mmol/l 4.5±0.4 4.4±0.3 6.9±1.2 6.5±1.9 6.1±1.7 4.8±1.3 4.5±0.3 4.6±0.3 6.6±1.0 6.1±1.6 5.9±1.3 4.5±1.1 - -
diameter
Dbase, mm 3.90±0.44 3.91±0.46 3.91±0.46 - 3.93±0.48 - 3.92±0.56 3.92±0.51 3.87±0.54 - 3.86±0.38 - 0.960 0.919
∆Dpeak, mm 0.22±0.12 0.22±0.10 0.19±0.09 - 0.21±0.13 - 0.22±0.10 0.23±0.10 0.20±0.12 - 0.22±0.13 - 0.675 0.550
∆Dpeak/Dbase, % 5.82±2.96 5.65±2.70 4.89±2.52 - 5.60±3.55 - 5.76±2.67 5.99±2.55 5.24±3.47 - 5.74±3.25 - 0.677 0.526
flow velocity
vbase, pxl 12±5 10±5 7±4 - 8±4 - 13±6 10±5 6±3 - 6±3 - 0.669 0.650
∆vpeak, pxl 44±13 44±12 42±14 - 50±16 - 48±14 46±13 44±15 - 47±16 - 0.617 0.530
∆vmean, pxl 10±4 10±4 8±3 - 11±4 - 11±3 10±3 9±4 - 10±4 - 0.374 0.341
∆vpeak/vbase, % 410±144 493±157 790±422 - 766±297 - 453±241 536±235 881±368 - 868±408 - 0.536 0.521
∆vmean/vbase, % 94±33 114±47 160±86 - 171±069 - 103±56 117±59 184±077 - 190±088 - 0.391 0.416
FMDv indices
(∆Dpeak/Dbase) /(∆vpeak/vbase) 0.016±0.012 0.012±0.006 0.008±0.006 - 0.009±0.007 - 0.017±0.013 0.014±0.010 0.008±0.007 - 0.008±0.007 - 0.589 0.565
(∆Dpeak/Dbase)/ (∆vmean/vbase) 0.079±0.060 0.057±0.034 0.039±0.025 - 0.037±0.026 - 0.076±0.058 0.068±0.051 0.035±0.030 - 0.038±0.033 - 0.521 0.530

Data are means ± SD and intra-class correlation coefficients (ICC); t, time moment in minutes, with t = - 40, t = -15 (for brachial flow-mediated dilation measurement) and t = 0 (for glucose) as time-points before glucose intake (i.e. fasting time-points) and t = 30, t = 60, t = 75 and t = 120 as time-points after glucose intake; ICC calculated over the fasting time-points by ANOVA; n = 22. Dbase, baseline diameter; ∆Dpeak, peak change in diameter; ∆Dpeak/Dbase is the %FMD measure; vbase, baseline flow velocity; ∆vpeak, peak change in flow velocity; ∆vmean, mean change in flow velocity; ∆vpeak/vbase, peak change in flow velocity relative to its baseline flow velocity; ∆vmean/vbase, mean change in flow velocity relative to its baseline flow velocity; ∆Dpeak/Dbase divided by ∆vpeak/vbase is pFMDv; ∆Dpeak/Dbase divided by ∆vmean/vbase is mFMDv; pxl, pixels.