Table 1. Blood glucose and brachial artery flow-mediated dilation parameters during session 1 and 2, and intra-class correlations.
Parameter | Session 1 | Session 2 | ICC | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
t = - 40 | t = - 15 / t = 0 | t = 30 | t = 60 | t = 75 | t = 120 | t = - 40 | t = -15 / t = 0 | t = 30 | t = 60 | t = 75 | t = 120 | Intra- session | Inter-session | |
Glucose, mmol/l | 4.5±0.4 | 4.4±0.3 | 6.9±1.2 | 6.5±1.9 | 6.1±1.7 | 4.8±1.3 | 4.5±0.3 | 4.6±0.3 | 6.6±1.0 | 6.1±1.6 | 5.9±1.3 | 4.5±1.1 | - | - |
diameter | ||||||||||||||
Dbase, mm | 3.90±0.44 | 3.91±0.46 | 3.91±0.46 | - | 3.93±0.48 | - | 3.92±0.56 | 3.92±0.51 | 3.87±0.54 | - | 3.86±0.38 | - | 0.960 | 0.919 |
∆Dpeak, mm | 0.22±0.12 | 0.22±0.10 | 0.19±0.09 | - | 0.21±0.13 | - | 0.22±0.10 | 0.23±0.10 | 0.20±0.12 | - | 0.22±0.13 | - | 0.675 | 0.550 |
∆Dpeak/Dbase, % | 5.82±2.96 | 5.65±2.70 | 4.89±2.52 | - | 5.60±3.55 | - | 5.76±2.67 | 5.99±2.55 | 5.24±3.47 | - | 5.74±3.25 | - | 0.677 | 0.526 |
flow velocity | ||||||||||||||
vbase, pxl | 12±5 | 10±5 | 7±4 | - | 8±4 | - | 13±6 | 10±5 | 6±3 | - | 6±3 | - | 0.669 | 0.650 |
∆vpeak, pxl | 44±13 | 44±12 | 42±14 | - | 50±16 | - | 48±14 | 46±13 | 44±15 | - | 47±16 | - | 0.617 | 0.530 |
∆vmean, pxl | 10±4 | 10±4 | 8±3 | - | 11±4 | - | 11±3 | 10±3 | 9±4 | - | 10±4 | - | 0.374 | 0.341 |
∆vpeak/vbase, % | 410±144 | 493±157 | 790±422 | - | 766±297 | - | 453±241 | 536±235 | 881±368 | - | 868±408 | - | 0.536 | 0.521 |
∆vmean/vbase, % | 94±33 | 114±47 | 160±86 | - | 171±069 | - | 103±56 | 117±59 | 184±077 | - | 190±088 | - | 0.391 | 0.416 |
FMDv indices | ||||||||||||||
(∆Dpeak/Dbase) /(∆vpeak/vbase) | 0.016±0.012 | 0.012±0.006 | 0.008±0.006 | - | 0.009±0.007 | - | 0.017±0.013 | 0.014±0.010 | 0.008±0.007 | - | 0.008±0.007 | - | 0.589 | 0.565 |
(∆Dpeak/Dbase)/ (∆vmean/vbase) | 0.079±0.060 | 0.057±0.034 | 0.039±0.025 | - | 0.037±0.026 | - | 0.076±0.058 | 0.068±0.051 | 0.035±0.030 | - | 0.038±0.033 | - | 0.521 | 0.530 |
Data are means ± SD and intra-class correlation coefficients (ICC); t, time moment in minutes, with t = - 40, t = -15 (for brachial flow-mediated dilation measurement) and t = 0 (for glucose) as time-points before glucose intake (i.e. fasting time-points) and t = 30, t = 60, t = 75 and t = 120 as time-points after glucose intake; ICC calculated over the fasting time-points by ANOVA; n = 22. Dbase, baseline diameter; ∆Dpeak, peak change in diameter; ∆Dpeak/Dbase is the %FMD measure; vbase, baseline flow velocity; ∆vpeak, peak change in flow velocity; ∆vmean, mean change in flow velocity; ∆vpeak/vbase, peak change in flow velocity relative to its baseline flow velocity; ∆vmean/vbase, mean change in flow velocity relative to its baseline flow velocity; ∆Dpeak/Dbase divided by ∆vpeak/vbase is pFMDv; ∆Dpeak/Dbase divided by ∆vmean/vbase is mFMDv; pxl, pixels.