Fig. 5. Supervised hierarchical clustering illustrates the effect of minocycline on expression apoptosis-related genes 6 and 12 hours after cortical ablation.
Expression of all probe sets were normalized to the average expression levels in the sham condition (N=4) prior to analysis. At 6 and 12 hours, saline treated animals (N=3) were compared to minocycline (N=3) animals using AVOVA. 15 genes showing differential expression > 1.5 fold (up or down) and with function relevant to apoptosis, underwent supervised hierarchical clustering.