Table 1.

Studies assessing complication rates from fiducial marker implantation for prostate image guided radiotherapy

Study	Patient numbers	Infective complications
Gill et al. [1]	234	3 patients (1.3%) required admission for sepsis
		1 patient (0.4%) had Grade 4 septicaemia.
Langenhuijsen et al. [2]	209	4 patients (1.9%) with fever received additional antibiotics.
		There were no hospital admissions.
Igdem et al. [3]	135	3 patients (2.2%) developed symptomatic urinary infection with fever and received antibiotics.
		There were no hospital admissions.
		1 (0.7%) patient developed asymptomatic bacteriuria resistant to antibiotic therapy.
Moman et al. [4]	402 had transrectal FM implantation	2 (0.5%) developed urosepsis (Grade 3 toxicity)
	512 had transperineal FM implantation	No grade 3 or 4 toxicity.
Loh et al.	285	22 patients (7.7%) received antibiotic treatment for a urinary infection
		8 patients (2.8%) required hospital admission for urosepsis.
TRUS biopsy series
Wagenlehner et al. [10]	521	5.2% had symptomatic urinary tract infection
		3.1% required hospital admissions for infectious complications

FM = fiducial marker.

TRUS = Transrectal ultrasound guided.