. Author manuscript; available in PMC: 2015 Feb 19.

Published in final edited form as: J Infect Dis. 2006 Sep 12;194(8):1127–1134. doi: 10.1086/507907

Table 2. Toll-interleukin 1 receptor domain containing adaptor protein (TIRAP) haplotype frequencies in the control and tuberculosis (TB) groups.

	Haplotype (G164A_G303A_C539T_C558T)
Group	GGCC 0000	GGCT 0001	GATC 0110	AGCC 1000
Control	577.8 (0.753)	24.0 (0.031)	7.2 (0.009)	158.2 (0.206)

All TB	481.5 (0.700)	51 (0.074)	5.5 (0.008)	149.5 (0.217)
All TB vs. control
OR (95% CI)	1	2.55 (1.55–4.20)	0.92 (0.30–2.80)	1.13 (0.88–1.46)
P		<.001	.88	.33

Pulmonary TB	250 (0.714)	19 (0.054)	1 (0.003)	80 (0.229)
Pulmonary TB vs. control
OR (95% CI)	1	1.83 (0.98–3.40)	0.32 (0.04–2.61)	1.17 (0.86–1.59)
P		.05	.26	.32

TBM	231.5 (0.686)	32 (0.095)	4.5 (0.013)	69.5 (0.206)
TBM vs. control
OR (95% CI)	1	3.33 (1.92–5.77)	1.56 (0.48–5.12)	1.10 (0.80–1.51)
P		<.001	.46	.57

NOTE Data are estimated haplotype no. (frequency), unless otherwise indicated. Haplotypes represent alleles composed of 4 TIRAP single-nucleotide polymorphisms: G164A_G303A_C539T_C558T. Odds ratios (ORs) were calculated in reference to the 0000 haplotype. “All TB” includes both pulmonary and meningeal TB (TBM). 0, common allele; 1, allele with minor frequency; CI, confidence interval.