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. 2015 Feb 18;10(2):e0116816. doi: 10.1371/journal.pone.0116816

Fig 2. Dose-dependent induction of MxA and 2’-5’OAS mRNA levels following treatment with recombinant IFN-α, IFN-λ1 and IFN-α +IFN-λ1.

Fig 2

A549 (a), (c) and HuH7 cells (b), (d) were exposed 3h to increasing amounts of either IFN type, alone or in combination, then mRNA levels for MxA (a), (b) and 2’-5’OAS (c), (d) were measured, expressed as fold induction vs. untreated cells. One out of three experiments is shown. Dotted lines: IFN-α (●) or IFN-λ1 (▲) used alone; continuous line: IFN-α and IFN-λ1 (■) used in combination.