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Representative TEM micrograph. HL-1 cardiomyocyte cell subjected to ischemia and reperfusion (IR) (left). Shown are mitochondria undergoing macroautophagy and micromitophagy. Mitochondria directly fused with the lysosomal membrane for degradation represent an example of microautophagy. A mitochondrion inside a lysosome is also seen on the right, providing an example of mitophagy in an ex vivo model of rat myocardial infarction. Left panel, bar = 1 μm; right panel, bar = 0.5 μm
