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. 2015 Feb 1;2015:712049. doi: 10.1155/2015/712049

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Copyright © 2015 Lampros Kousoulas et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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(a) The ROC-curve for age in years is shown for the prediction of mortality during follow-up. The area under the curve (AUROC) indicates potential prognostic value (AUROC = 0.723; 95% CI: 0.588–0.857). Multivariate Cox regression revealed age as a significant independent risk factor for mortality during follow-up. The cut-off value for age in years at last transplant chosen with the best Youden index for the prediction of mortality was 43 years. (b) Survival of patients who are ≤ 43 years old is significantly superior as compared to those who are older than 43 years at the time of their last kidney transplant (P = 0.005; Kaplan-Meier survival analysis, log rank test).