Fig 5. BN.ACI-Renag1 congenic rats exhibit the same spectrum and incidence of urogenital anomalies as ACI rats.

The Con1 and Con2 congenic rat strains were generated as described in Materials and Methods. Each strain is homozygous for ACI alleles across the Renag1 interval. A. The incidence of all grossly discernable urogenital anomalies in ACI (n = 216), Con1 (n = 238) and Con2 (n = 298) rats is illustrated. Numeral 1 indicates statistically significant difference relative to ACI. B. The frequency of unilateral renal agenesis (URA), unilateral renal hypoplasia (URH) and hydroureteronephrosis (HUN) in ACI, Con1 and Con2 rats is illustrated as a percent of total urogenital anomalies. C. The frequency of URA in ACI, Con1 and Con2 rats observed on the left (L) versus right (R) sides is illustrated. The asterisk indicates a statistically significant right side bias.