Figure 3. Serum biochemistry and serum level of PINP of wild-type and Fgfr2 S252W/+mice at 2 months and 5 months.
(A) There was no remarkable difference in total serum Ca or phosphate between wild-type and mutant mice at 2 months or at 5 months. (n = 6). (B) The serum levels of PINP as measured by ELISA were significantly lower in mutant mice at 2 months than in wild-type mice at 2 months. (C) These levels were significantly higher in mutant mice at 5 months than in wild-type mice at 5 months (n = 6). Graphs show mean value ±SD (Student's t-test, **P<0.01).
