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. 2014 Dec 17;43(2):893–903. doi: 10.1093/nar/gku1334

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© The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Replication fork restart for fancb^Δex2 cells mutated for Recql5 or Blm. Refer to Supplementary Table S2 for statistics. These data are the average of a single experiment. For no treatment, the number of total fibers counted [restart, stalled and new origin]: AB2.2 control: 926 total [809 (87.37%), 100 (10.8%), 17 (1.84%)], fancb^Δex2: 1497 [1304 (87.11%), 162 (10.82%), 31 (2.07%)], recql5^−/−: 2137 total [1862 (87.13%), 234 (10.95%), 41 (1.92%)], fancb^Δex2 recql5^−/−:1752 [1498 (85.5%), 214 (12.21%), 46 (2.2%). blm^−/−: 2135 total [1878 (87.7%), 216 (10.1%), xx (xx%)], fancb^Δex2 blm^−/−:1843 [1615 (88.6%), 194 (10.5%), 34 (1.8%)]. For HU treatment the number of fibers counted [restart, stalled and new origin]: AB2.2 control: 1809 [1516 (83.80%), 256 (13.93%), 41 (2.27%)], fancb^Δex2: 2031 [1460 (71.89%), 516 (25.41%), 55 (2.71%)], recql5^−/−: 2670 [1976 (74.04%), 638 (23.9%), 56 (2.1%)], fancb^Δex2 recql5^−/−: 2363 [1491 (63.1%), 798 (33.77%), 74 (3.13%)]. blm^−/−: 1554 total [1136 (78.1%), 388 (25%), 30 (1.9%)], fancb^Δex2 blm^−/−:1880 [1374 (73.1%), 467 (24.8%), 39 (2.1%)].