FIG 3.
Effects of deletion of acuK and acuM on induction of pulmonary epithelial cell damage. The A549 pulmonary epithelial cell line was infected with the indicated strains of A. fumigatus for 20 h, after which the extent of epithelial cell damage was assessed by a 51Cr release assay. Results are means ± SDs from 3 independent experiments, each performed in triplicate. *, P < 0.01 compared to the wild-type strain; †, P < 0.01 compared to the ΔacuK+acuK complemented strain; ‡, P < 0.04 compared to the ΔacuK mutant.