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Susceptibility to α-defensins of C. difficile strains belonging to different PCR ribotypes. Bacterial suspensions were tested against 7 μM HD5 (A) and HNP1 (B) or control peptide (data not shown) for 2 h at 37°C. Values are means ± SEMs for C. difficile hypervirulent and other epidemic PCR ribotypes, E. coli ATCC 25922, and E. faecalis ATCC 29212. P values were calculated by the Wilcoxon Mann-Whitney rank sum 2-tailed test.
