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. 2015 Jan 13;112(4):630–635. doi: 10.1038/bjc.2014.647

Table 2. Survival estimates by patient characteristics.

  N Patients N Events 5-year overall survival estimate (95% CI) P-value N Events 5-year relapse-tree survival estimate (95% CI) P-value
All patients
589
38
0.93 (0.9, 0.95)
 
61
0.87 (0.84, 0.9)
 
Year of diagnosis
2001–2006 142 14 0.92 (0.86, 0.96)   19 0.88 (0.82, 0.93)  
2007–2012
447
24
0.93 (0.89, 0.95)
0.60
42
0.86 (0.8, 0.9)
0.64
Age (years)
Age≤50 293 19 0.93 (0.88, 0.96)   30 0.87 (0.82, 0.91)  
Age>50
296
19
0.92 (0.88, 0.95)
0.78
31
0.87 (0.82, 0.91)
0.80
Race/ethnicity
White 344 23 0.92 (0.88, 0.95)   33 0.89 (0.85, 0.92)  
Black 73 6 0.89 (0.77, 0.95)   13 0.72 (0.55, 0.84)  
Hispanic 116 4 0.98 (0.92, 0.99)   7 0.92 (0.83, 0.96)  
Other
56
5
0.87 (0.71, 0.95)
0.39
8
0.84 (0.71, 0.92)
0.03
Clinical stage
I–II 301 17 0.93 (0.89, 0.96)   22 0.9 (0.85, 0.94)  
III
282
20
0.92 (0.87, 0.95)
0.42
38
0.84 (0.79, 0.88)
0.01
Histology
Ductal 543 34 0.93 (0.9, 0.95)   54 0.88 (0.84, 0.91)  
Other
46
4
0.91 (0.74, 0.97)
0.56
7
0.82 (0.64, 0.92)
0.26
Nuclear grade
1–2 123 7 0.93 (0.84, 0.97)   14 0.86 (0.76, 0.92)  
3
452
30
0.93 (0.89, 0.95)
0.57
45
0.88 (0.84, 0.91)
0.71
Lymphovascular invasion
Negative 479 24 0.94 (0.91, 0.96)   37 0.9 (0.87, 0.93)  
Positive
110
14
0.86 (0.76, 0.92)
0.002
24
0.72 (0.6, 0.81)
<0.0001
Hormone receptor status
Negative 236 18 0.92 (0.86, 0.95)   24 0.88 (0.82, 0.92)  
Positive
348
20
0.93 (0.89, 0.96)
0.53
36
0.87 (0.82, 0.91)
0.77
Pathologic complete response
No 386 33 0.9 (0.85, 0.93)   54 0.83 (0.78, 0.87)  
Yes
203
5
0.98 (0.93, 0.99)
0.002
7
0.95 (0.9, 0.98)
<0.0001
Adjuvant trastuzumab
No 109 11 0.91 (0.84, 0.95)   12 0.92 (0.85, 0.96)  
Yes
480
27
0.93 (0.9, 0.95)
0.97
49
0.85 (0.8, 0.89)
0.33
Adjuvant radiation
No 125 8 0.94 (0.86, 0.97)   10 0.89 (0.79, 0.95)  
Yes
464
30
0.92 (0.89, 0.95)
0.69
51
0.87 (0.83, 0.9)
0.63
Adjuvant endocrine therapy
No 301 23 0.91 (0.87, 0.94)   31 0.87 (0.82, 0.91)  
Yes 288 15 0.94 (0.89, 0.96) 0.17 30 0.87 (0.82, 0.91) 0.84

Abbreviation: CI=confidence interval.