Table 2D. Prognostic values of Osteopontin staining: multivariate analysis for the various measures of Osteopontin staining, focusing on nuclear Osteopontin-c intensity and cytoplasmic Osteopontin–exon 4 intensity as predictors of patient survival.
|
|
95% CI |
|
||
---|---|---|---|---|---|
Odds ratio | P-value | Lower | Upper | AIC | |
OPNc nucl.int. |
1.45 |
0.01 |
1.10 |
1.93 |
468.9 |
OPNc nucl.per. |
1.00 |
0.36 |
0.99 |
1.01 |
— |
OPNc nucl.int. |
1.40 |
0.02 |
1.05 |
1.86 |
468.7 |
pan-OPN nucl.int. |
0.68 |
0.03 |
0.48 |
0.97 |
— |
OPNc nucl.int. |
1.43 |
0.01 |
1.08 |
1.91 |
473.6 |
pan-OPN cyt.int. |
1.02 |
0.93 |
0.70 |
1.48 |
— |
OPNc nucl.int. |
1.32 |
0.04 |
1.02 |
1.72 |
341.9 |
Exon 4 cyt.int. |
1.69 |
0.01 |
1.24 |
2.34 |
— |
Exon 4 cyt.per. |
1.01 |
0.03 |
1.00 |
1.02 |
345.9 |
OPNc nucl.per. |
1.00 |
0.38 |
0.99 |
1.01 |
— |
Exon 4 cyt.int. |
2.01 |
<0.01 |
1.40 |
2.92 |
339.8 |
Exon 4 cyt.per. | 0.99 | 0.54 | 0.98 | 1.01 |
Abbreviations: AIC=Akaike Information Criterion; CI=confidence interval; cyt.int.=cytosolic intensity; cyt.per.=cytosolic per cent positivity; nucl.int.=nuclear intensity; nucl.per.=nuclear per cent positivity; OPNc=Osteopontin-c.