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. 2015 Jan 27;112(4):729–738. doi: 10.1038/bjc.2014.664

Table 2D. Prognostic values of Osteopontin staining: multivariate analysis for the various measures of Osteopontin staining, focusing on nuclear Osteopontin-c intensity and cytoplasmic Osteopontin–exon 4 intensity as predictors of patient survival.

   
 
95% CI
 
  Odds ratio P-value Lower Upper AIC
OPNc nucl.int.
1.45
0.01
1.10
1.93
468.9
OPNc nucl.per.
1.00
0.36
0.99
1.01

OPNc nucl.int.
1.40
0.02
1.05
1.86
468.7
pan-OPN nucl.int.
0.68
0.03
0.48
0.97

OPNc nucl.int.
1.43
0.01
1.08
1.91
473.6
pan-OPN cyt.int.
1.02
0.93
0.70
1.48

OPNc nucl.int.
1.32
0.04
1.02
1.72
341.9
Exon 4 cyt.int.
1.69
0.01
1.24
2.34

Exon 4 cyt.per.
1.01
0.03
1.00
1.02
345.9
OPNc nucl.per.
1.00
0.38
0.99
1.01

Exon 4 cyt.int.
2.01
<0.01
1.40
2.92
339.8
Exon 4 cyt.per. 0.99 0.54 0.98 1.01  

Abbreviations: AIC=Akaike Information Criterion; CI=confidence interval; cyt.int.=cytosolic intensity; cyt.per.=cytosolic per cent positivity; nucl.int.=nuclear intensity; nucl.per.=nuclear per cent positivity; OPNc=Osteopontin-c.