Table 3. Haematologic toxicity in course 1 of therapy (n=32).
| 555 MBq kg−1 (15 mCi kg−1) N=6 | 666 MBq kg−1 (18 mCi kg−1) N=26 | Both Dose Levels N=32 | |
|---|---|---|---|
| ANC nadir <500 mm−3 |
5 (83%) |
21 (81%) |
26 (81%) |
| Platelet nadir <20 000 mm−3 |
1 (17%) |
14 (54%) |
15 (47%) |
| Median days ANC recoverya (range) |
10 (9–27) |
8 (2–24) |
9 (2–27) |
| Median days platelet recoveryb (range) | 18c | 14 (9–39) | 14 (9–39) |
Abbreviation: ANC=absolute neutrophil count.
a
Days from stem cell infusion to ANC >500 mm−3 for patients with ANC nadir <500 mm−3.
b
Days from stem cell infusion to platelets >20 000 mm−3 for patients with platelet nadir <20 000 mm−3.
c
Data for one patient only.