Table 3.
HLA-G
Genotypes* |
NT (n=14 4) |
IP- TR (n=2 9) |
IU- TR (n=19) |
IU- TR (n=4 3) |
IP-TR vs. NT | IU-TR vs. NT | IU2-TR vs. NT | |||
---|---|---|---|---|---|---|---|---|---|---|
OR (95% CI) |
P | OR (95% CI) |
P | OR (95% CI) |
P | |||||
G*01:01:01/G*01
:01:01 |
17 (11.81 ) |
3 (10.3 4) |
5 (26.32 ) |
5 (11.6 3) |
0.86 (0.23- 3.16) |
1.00 0 |
2.66 (0.85- 8.34) |
0.14 3 |
0.98 (0.34- 2.84) |
1.00 0 |
G*01:01:01/G*01
:01:02 |
15 (11.81 ) |
4 (13.7 9) |
3(15.7 9) |
4 (9.30 ) |
1.37 (0.42- 4.49) |
0.74 4 |
1.61 (0.42- 6.18) |
0.69 8 |
0.88 (0.27- 2.81) |
1.00 0 |
G*01:01:01/G*01
:01:09 |
4 (2.78) |
0 (0.00 ) |
1 (5.26) |
1 (2.33 ) |
- | 0.60 8 |
1.94 (0.21- 18.3) |
1.00 0 |
0.83 (0.09- 7.65) |
1.00 0 |
G*01:01:01/G*01
:03:01 |
4 (2.78) |
0 (0.00 ) |
1 (5.26) |
2 (4.65 ) |
- | 0.60 8 |
1.94 (0.21- 18.3) |
1.00 0 |
1.71 (0.30- 9.66) |
0.62 2 |
G*01:01:01/G*01
:04:01 |
3 (2.08) |
2 (6.90 ) |
0 (0.00) |
0 (0.00 ) |
3.48 (0.56- 21.8) |
0.19 6 |
- | 1.00 0 |
- | 0.58 7 |
G*01:01:01/G*01
:04:04 |
17 (11.81 ) |
4 (13.7 9) |
0 (0.00) |
6 (13.9 5) |
1.19 (0.37- 3.85) |
0.75 8 |
- | 0.22 4 |
1.21 (0.44- 3.29) |
0.79 2 |
G*01:01:01/G*01
:05N |
7 (4.86) |
1 (3.45 ) |
0 (0.00) |
0 (0.00 ) |
0.70 (0.08- 5.91) |
1.00 0 |
- | 0.60 2 |
- | 0.20 5 |
G*01:01:02/G*01
:01:02 |
6 (4.17) |
2 (6.90 ) |
3 (15.79 ) |
4 (9.30 ) |
1.70 (0.33- 8.89) |
0.62 3 |
4.31 (0.98- 18.9) |
0.07
2 |
2.35 (0.63- 8.77) |
0.24 2 |
G*01:01:02/G*01
:01:08 |
3 (2.08) |
1 (3.45 ) |
0 (0.00) |
1 (2.33 ) |
1.67 (0.17- 16.7) |
1.00 0 |
- | 1.00 0 |
1.11 (0.11- 11.0) |
1.00 0 |
G*01:01:02/G*01
:01:19 |
4 (2.78) |
0 (0.00 ) |
0 (0.00) |
0 (0.00 ) |
- | 0.60 8 |
- | 1.00 0 |
- | 0.57 5 |
G*01:01:02/G*01
:03:01 |
4 (2.78) |
0 (0.00 ) |
2 (10.53 ) |
5 (11.6 3) |
- | 0.60 8 |
4.11 (0.70- 24.1) |
0.14 5 |
4.61 (1.17- 17.9) |
0.03
1 |
G*01:01:02/G*01
:04:01 |
3 (2.08) |
0 (0.00 ) |
0 (0.00) |
1 (2.33 ) |
- | 1.00 0 |
- | 1.00 0 |
1.11 (0.11- 11.0) |
1.00 0 |
G*01:01:02/G*01
:04:04 |
10 (6.94) |
2 (6.90 ) |
2 (10.53 ) |
4 (9.30 ) |
1.00 (0.21- 4.78) |
1.00 0 |
1.57 (0.32- 7.81) |
0.63 4 |
1.37 (0.41- 4.62) |
0.74 1 |
G*01:01:02/G*01
:05N |
6 (4.17) |
0 (0.00 ) |
0 (0.00) |
2 (4.65 ) |
- | 0.38 7 |
- | 0.61 5 |
1.12 (0.22- 5.77) |
1.00 0 |
G*01:01:08/G*01
:04:04 |
3 (2.08) |
0 (0.00 ) |
1 (5.26) |
1 (2.33 ) |
- | 1.00 0 |
2.61 (0.26- 26.5) |
0.39 4 |
1.11 (0.11- 11.0) |
1.00 0 |
G*01:01:09/G*01
:05N |
3 (2.08) |
0 (0.0 0) |
0 (0.00) |
0 (0.00 ) |
- | 1.00 0 |
- | 1.00 0 |
- | 0.58 7 |
G*01:03:01/G*01
:04:04 |
3 (2.08) |
1 (3.45 ) |
0 (0.00) |
0 (0.00 ) |
1.67 (0.17- 16.7) |
1.00 0 |
- | 1.00 0 |
- | 0.58 7 |
G*01:03:01/G*01
:05N |
4 (2.78) |
0 (0.00 ) |
0 (0.00) |
0 (0.00 ) |
- | 0.60 8 |
- | 1.00 0 |
- | 0.57 5 |
G*01:04:04/G*01
:04:04 |
6 (4.17) |
0 (0.00 ) |
0 (0.00) |
0 (0.00 ) |
- | 0.38 7 |
- | 0.61 5 |
- | 0.33 9 |
G*01:04:04/G*01
:05N |
6 (4.17) |
1 (3.45 ) |
0 (0.00) |
2 (4.65 ) |
0.82 (0.09- 7.09) |
1.00 0 |
- | 0.61 5 |
1.12 (0.22- 5.77) |
1.00 0 |
indicates HLA-G genotype frequencies > 2% in the NT group. NT: HIV-1 nontransmitting mother; IP-TR: intrapartum HIV-1 transmitting mother; IU-TR: in utero HIV-1 transmitting mother; IU2-TR: enriched group of presumed in utero transmitting mothers. Highlighted and bold P values indicate significant differences (P<0.05) and bold P values indicate trends (P<0.090).