Table 6.

Significant linkage disequilibrium (LD) between HLA-G alleles, the 14-bp indel, 3’UTR SNPs and haplotypes in HIV-1 positive mothers (n=216)

LD comparisons		N	(%)	D'	X2	P-value
G*01:01:01	Del	126	29.17	0.95	45.19	<0.001
	UTR1	44	10.19	0.80	37.70	<0.001
	UTR4	33	7.64	0.64	19.97	<0.001
	UTR6	45	10.42	0.94	47.47	<0.001
	UTR20	6	1.39	1.00	5.93	<0.05
G*01:01:02	Ins	96	22.22	1.00	66.88	<0.001
	UTR2	96	22.22	1.00	98.49	<0.001
G*01:01:19	Ins	14	3.24	1.00	6.98	<0.01
	UTR2	14	3.24	1.00	10.27	<0.01
G*01:03:01	Ins	33	7.64	1.00	17.64	<0.001
	UTR5	33	7.64	1.00	189.72	<0.001
G*01:04:01	Del	17	3.94	1.00	4.16	<0.05
	UTR3	17	3.94	1.00	27.24	<0.001
G*01:04:04	Del	78	18.06	1.00	24.37	<0.001
	UTR3	78	18.06	1.00	159.40	<0.001
G*01:05N	Ins	33	7.64	1.00	17.64	<0.001
	UTR2	33	7.64	1.00	25.98	<0.001
	UTR7	1	0.23	1.00	5.83	<0.05
Del	+3003 C	44	10.19	1.00	11.94	<0.01
	+3010 G	148	34.26	1.00	65.44	<0.001
	+3035 C	245	56.71	1.00	7.30	<0.05
	+3142 C	148	34.26	1.00	65.44	<0.001
	+3187 G	51	11.81	1.00	14.23	<0.001
	+3196 C	245	56.71	1.00	126.48	<0.001
Ins	+3003 T	187	43.29	1.00	4.78	<0.05
	+3010 C	187	43.29	1.00	60.58	<0.001
	+3035 T	38	8.80	1.00	20.71	<0.001
	+3142 G	187	43.29	1.00	60.58	<0.001
	+3187 A	187	43.29	1.00	6.44	<0.01
	+3196 G	149	34.49	1.00	136.23	<0.001

N: the number of individuals; D’: measure of linkage disequilibrium; X²: Chi-Square value from which the P-value was determined significant at P<0.05.