Table 1. Measurements of secreted mucus in mice during bronchoconstriction.

Histological measurement	WT	Muc5ac −/−	p-value
Vmucus per surface area (mm3 cm−2)
All airways	0.71±0.08	0.48±0.43	0.313
Axial bronchi	1.16±0.09	0.84±0.11*	0.032*
Non-terminal bronchioles	0.58±0.13	0.30±0.06*	0.041*
Vmucus per anatomic region (mm3 mm−3)
All airways	3.9±1.1	2.3±0.6	0.185
Axial bronchi	0.8±0.1	0.6±0.2	0.122
Non-terminal bronchioles	3.1±1.0	1.7±0.5*	0.099
% occlusion per anatomic region
All airways	18±4.3	7.2±1.4	0.020*
Axial bronchi	20.1±5.7	11.7±2.6	0.097
Non-terminal bronchioles	16.8±1.3	6.3±1.2	0.022*

Values are means ± s.e.m.

^*p < 0.05 by unpaired t-test. N = 4 WT and 5 Muc5ac^−/− mice.