Table 1.
Population demographics and pre-transplant characteristics in 785 liver transplant recipients
| Variables | Body mass index, kg/m2 | P-value | |||||
|---|---|---|---|---|---|---|---|
| <18.0 (n = 9) | 18.0–24.9 (n = 210) | 25.0–29.9 (n = 294) | 30.0–35.0 (n = 169) | 35.1–40.0 (n = 77) | >40.0 (n = 26) | ||
| Age, years, median | 46 | 55 | 55 | 56 | 56 | 53 | 0.349 |
| Male, % | 4 (44.4) | 134 (63.8) | 214 (72.8) | 119 (70.4) | 47 (61.0) | 10 (37.0) | 0.001 |
| White, % | 7 (0.78) | 171 (81.4) | 249 (84.7) | 148 (87.6) | 68 (88.3) | 13 (73.1) | 0.267 |
| Comorbidities, % | |||||||
| Diabetes | 3 (33.3) | 44 (21.0) | 76 (25.9) | 51 (30.2) | 25 (32.5) | 6 (23.1) | 0.277 |
| Hypertension | 1 (11.1) | 49 (23.3) | 85 (28.9) | 59 (34.9) | 31 (40.3) | 14 (53.8) | <0.0001 |
| Coronary artery disease | 0 (0) | 6 (2.9) | 20 (6.8) | 9 (5.3) | 6 (7.8) | 2 (7.7) | 0.311 |
| Other cardiac disease | 0 (0) | 15 (7.1) | 26 (8.8) | 16 (9.5) | 10 (13.0) | 3 (11.5) | 0.621 |
| Renal insufficiency | 2 (22.2) | 27 (12.9) | 52 (17.7) | 26 (15.4) | 19 (24.7) | 1 (3.8) | 0.089 |
| Renal failure on dialysis | 2 (22.2) | 19 (9.0) | 23 (7.8) | 18 (10.7) | 11 (14.3) | 2 (7.7) | 0.497 |
| Aetiology of liver disease, % | |||||||
| Hepatitis C virus | 3 (33.3) | 80 (38.1) | 149 (50.7) | 78 (46.2) | 31 (40.3) | 12 (46.2) | 0.102 |
| Non-alcoholic steatohepatitis | 0 (0.0) | 2 (0.9) | 19 (6.5) | 14 (8.3) | 17 (22.8) | 6 (23.1) | <0.0001 |
| Alcohol (primary diagnosis) | 4 (44.4) | 32 (15.2) | 35 (11.9) | 21 (12.4) | 12 (15.6) | 2 (7.7) | 0.082 |
| Alcohol (secondary diagnosis) | 0 | 13 (6.2) | 25 (8.5) | 14 (8.3) | 9 (11.7) | 1 (3.8) | 0.543 |
| Primary biliary cirrhosis | 0 | 16 (7.6) | 14 (4.8) | 4 (2.4) | 2 (2.6) | 1 (3.8) | 0.15 |
| Primary sclerosing cholangitis | 1 (11.1) | 18 (8.6) | 11 (3.7) | 4 (2.4) | 1 (1.3) | 0 | 0.012 |
| Other | 1 (11.1) | 62 (29.5) | 66 (22.4) | 48 (28.4) | 14 (18.2) | 5 (19.2) | 0.176 |
| Hepatocellular carcinoma | 0 (0.0) | 81 (38.6) | 110 (37.4) | 61 (36.1) | 29 (37.7) | 7 (26.9) | 0.836 |
| Other | |||||||
| MELD score, lab-based, median | 28 | 18 | 19 | 20 | 24 | 23 | 0.002 |
| Waiting time, days, median | 25 | 59 | 59 | 89 | 82 | 72 | 0.011 |
| Liver and kidney transplant, % | 1 (11.1) | 11 (5.2) | 13 (4.4) | 6 (3.6) | 4 (5.2) | 0 (0) | 0.719 |
MELD, Model for End-stage Liver Disease.