Table 1.
Demographic and group characteristics.
| Control | AD | DLB | Statistic, P value | |
|---|---|---|---|---|
| n | 39 | 47 | 41 | |
| Gender (m: f) | 25: 14 | 33: 14 | 26: 15 | χ2=0.6, 0.8 |
| Age (years) | 77.0±6.4 | 79.0±8.8 | 78.6±6.2 | F2,124=0.8, 0.4 |
| MMSE | 29.0±1.0 | 20.8±4.0 | 20.9±5.0 | F2,124=62.0, <0.001† |
| CAMCOG | 96.5±3.3 | 67.8±13.5 | 69.5±14.9 | F2,124=74.1, <0.001† |
| NPI total | Na | 9.3±8.7 | 13.5±11.0 | U88=1026.5, 0.04 |
| NPI_hall | Na | 0.2±0.8 | 2.1±2.1 | U88=1521.0, <0.001 |
| RBD (y: n) | 0: 39 | 1: 46 | 23: 18 | χ2=22.6, <0.001⁎ |
| UPDRS III | 1.2±1.7 | 2.6±2.4 | 24.4±13.7 | H2=86.1, <0.001†† |
| CAF | Na | 1.5±3.0 | 5.9±4.7 | U88=1380.5, <0.001 |
| ChI use (y: n) | Na | 40: 7 | 32: 9 | χ2=0.7, 0.4 |
| TIVspm8 (ml) | 1500.0±133.8 | 1495.4±134.0 | 1525.0±154.4 | F2,124=0.4, 0.6 |
Bold text denotes statistical significance.
Values expressed as Mean±1 S.D.
MMSE=Mini Mental State Examination, CAMCOG=Cambridge Cognitive Examination, NPI=Neuropsychiatric Inventory, NPI_hall=NPI hallucinations, RBD=REM sleep behaviour disorder, UPDRS III=Unified Parkinson׳s Disease Rating Scale (section III), ChI=cholinesterase inhibitor, TIV=total intracranial volume. CAF=Clinical Assessment of Fluctuation. Na=not applicable.
Post-hoc tests:
⁎
AD vs. DLB.
†
Con>AD, DLB (P<0.001), AD vs. DLB (P>0.10) (Gabriel׳s).
††
DLB>Con, AD (P<0.001), Con vs. AD (P=0.14) (Mann–Whitney U).