Table 2.
Association between morphological features and fibrosis grade in NASH biopsies according to Bedossa's histological algorithm.
| Morphological features | Fibrosis | P value | ||||
|---|---|---|---|---|---|---|
| Absent | Stage 1 | Stage 2 | Stage 3 | Stage 4 | ||
| Steatosis degrees | P = 0.782 | |||||
| 1 | 4 (33.33%) | 3 (25%) | 2 (16.67%) | 3 (25%) | 0 | |
| 2 | 5 (23.82%) | 6 (28.57%) | 6 (28.57%) | 2 (9.52%) | 2 (9.52%) | |
| 3 | 2 (18.19%) | 3 (27.27%) | 4 (6.36%) | 1 (9.09%) | 1 (9.09%) | |
| Ballooning | P = 0.252 | |||||
| Few | 7 (24.14%) | 10 (34.48%) | 6 (20.69%) | 5 (17.24%) | 1 (3.45%) | |
| Frequent | 4 (26.67%) | 2 (13.33%) | 6 (40%) | 1 (6.67%) | 2 (13.33%) | |
| Lobular inflammation | P < 0.001 | |||||
| <2 foci/field | 11 (39.29%) | 8 (28.57%) | 6 (21.43%) | 2 (7.14%) | 1 (3.57%) | |
| 2–4 foci/field | 0 | 4 (25%) | 6 (37%) | 4 (25%) | 2 (12.5%) | |