Table 1.
Morphologic parameter | Histological grading of malignancy of tumor cell population | |||
---|---|---|---|---|
1 | 2 | 3 | 4 | |
Degree of keratinization | Highly keratinized (>50% of the cells) | Moderately keratinized (20–50% of the cells) | Minimal keratinization (5–20% of the cells) | No keratinization (0–5% of the cells) |
| ||||
Nuclear polymorphism | Little nuclear polymorphism (>75% mature cells) | Moderately abundant nuclear polymorphism (50–75% mature cells) |
Abundant nuclear polymorphism (25–50% mature cells) | Extreme nuclear polymorphism (0–25% mature cells) |
| ||||
Number of mitoses/HPF | 0-1 | 2-3 | 4-5 | >5 |
| ||||
Pattern of invasion | Pushing well-delineated infiltrating borders | Infiltrating, solid cords, bands and/or strands | Small groups or cords of infiltrating cells (n > 15) | Marked and wide spread cellular dissociation in small groups of cells (n < 15) and/or in single cells |
| ||||
Lymphoplasmacytic infiltration | Marked | Moderate | Slight | None |