. Author manuscript; available in PMC: 2015 Feb 19.

Published in final edited form as: J Alzheimers Dis. 2015 Jan 1;44(2):585–598. doi: 10.3233/JAD-141937

Table 3.

Between group differences in MD: Frontal, Parietal, Cerebellum

Region	df	F	NC mean (SE) MCI mean (SE) AD mean (SE)	P	Bonferroni-corrected two-way comparisons within each region
Left Superior Frontal Gyrus	2	5.91	1.18e-3 (6.21e-6)	0.005	0.025 (NC-AD), 0.006 (MCI-AD)
			1.17e-3 (8.48e-6)
			1.21e-3 (8.73e-6)
Left Middle Frontal Gyrus	2	7	1.18e-3 (7.67e-6)	0.002	0.004 (NC-AD), 0.005 (MCI-AD)
			1.18e-3 (11.0e-6)
			1.22e-3 (11.0e-6)
Left Inferior Frontal Gyrus	2	6.41	1.09e-3 (7.25e-6)	0.003	0.003 (NC-AD), 0.023 (MCI-AD)
			1.10e-3 (9.11e-6)
			1.13e-3 (9.34e-6)
Left Superior Frontal Gyrus White Matter	2	4.09	0.82e-3 (7.47e-6)	0.021
			0.82e-3 (6.78e-6)
			0.85e-3 (12.2e-6)
Left Middle Frontal Gyrus White Matter	2	4.80	0.82e-3 (7.4e-6)	0.011
			0.81e-3 (7.83e-6)
			0.85e-3 (11.3e-6)
Left Inferior Frontal Gyrus White Matter	2	3.89	0.82e-3 (7.65e-6)	0.025
			0.83e-3 (9.79e-6)
			0.862e-3 (12.5e-6)
Left Lateral Fronto-Orbital Gyrus	2	3.01	1.11e-3 (8.97e-6)	0.056
			1.13e-3 (13.5e-6)
			1.16e-3 (16.0e-6)
Left Middle Fronto-Orbital Gyrus	2	5.48	1.09e-3 (10.8e-6)	0.006	0.005 (NC-AD)
			1.12e-3 (13.9e-6)
			1.15e-3 (17.9e-6)
Left Lateral Fronto-Orbital Gyrus White Matter	2	2.67	0.86e-3 (8.57e-6)	0.077
			0.87e-3 (12.7e-6)
			0.89e-3 (13.5e-6)
Left Middle Fronto-Orbital Gyrus White Matter	2	2.68	0.88e-3 (9.47e-6)	0.076
			0.89e-3 (12.3e-6)
			0.92e-3 (17.6e-6)
Left Gyrus Rectus	2	5.50	1.12e-3 (11.5e-6)	0.006	0.008 (NC-AD), 0.030 (MCI-AD)
			1.12e-3 (12.9e-6)
			1.18e-3 (17.0e-6)
Left Gyrus Rectus White Matter	2	2.61	0.87e-3 (7.63e-6)	0.081
			0.87e-3 (12.4e-6)
			0.90e-3 (14.4e-6)
Right Superior Frontal Gyrus	2	4.42	1.17e-3 (6.64e-6)	0.016
			1.16e-3 (8.72e-6)
			1.20e-3 (12.4e-6)
Right Middle Frontal Gyrus	2	5.55	1.15e-3 (8.57e-6)	0.006	0.014 (NC-AD), 0.014 (MCI-AD)
			1.15e-3 (10.2e-6)
			1.20e-3 (13.5e-6)
Right Inferior Frontal Gyrus	2	4.62	1.08e-3 (9.33e-6)	0.013
			1.08e-3 (8.22e-6)
			1.12e-3 (12.9e-6)
Right Superior Frontal Gyrus White Matter	2	3.34	1.17e-3 (6.64e-6	0.042
			1.16e-3 (8.72e-6)
			1.20e-3 (12.4e-6)
Right Middle Frontal Gyrus White Matter	2	4.00	1.15e-3 (8.57e-6)	0.023
			1.15e-3 (10.2e-6)
			1.19e-3 (13.5e-6)
Right Inferior Frontal Gyrus White Matter	2	3.65	1.08e-3 (9.33e-6)	0.032
			1.08e-3 (8.22e-6)
			1.12e-3 (12.9e-6)
Right Lateral Fronto-Orbital Gyrus	2	4.35	1.11e-3 (9.82e-6)	0.017
			1.11e-3 (11.1e-6)
			1.16e-3 (19.1e-6)
Right Middle Fronto-Orbital Gyrus	2	4.05	1.07e-3 (11.0e-6)	0.022
			1.09e-3 (12.6e-6)
			1.14e-3 (25.0e-6)
Right Lateral Fronto-Orbital Gyrus White Matter	2	1.13	0.87e-3 (21.8e-6)	0.329
			0.84e-3 (7.87e-6)
			0.84e-3 (9.72e-6)
Right Middle Fronto-Orbital Gyrus White Matter	2	0.63	0.87e-3 (10.3e-6)	0.534
			0.87e-3 (12.1e-6)
			0.89e-3 (21.2e-6)
Right Gyrus Rectus	2	8.35	1.10e-3 (10.4e-6)	<0.001	0.010 (NC-AD), 0.007 (MCI-AD)
			1.11e-3 (11.9e-6)
			1.17e-3 (17.6e-6)
Right Gyrus Rectus White Matter	2	6.10	0.86e-3 (7.98e-6)	0.0034	0.007 (NC-AD), 0.012 (MCI-AD)
			0.86e-3 (9.97e-6)
			0.92e-3 (21.9e-6)
Left Superior Parietal Gyrus	2	1.25	1.13e-3 (8.51e-6)	0.293
			1.12e-3 (11.7e-6)
			1.15e-3 (12.9e-6)
Left Superior Parietal Gyrus White Matter	2	2.76	0.82e-3 (11.4e-6)	0.071
			0.80e-3 (6.70e-6)
			0.83e-3 (14.6e-6)
Left Pre-cuneus	2	1.10	1.21e-3 (14.1e-6)	0.338
			1.20e-3 (18.4e-6)
			1.23e-3 (18.0e-6)
Left Pre-cuneus White Matter	2	3.28	0.82e-3 (13.1e-6)	0.044
			0.81e-3 (9.73e-6)
			0.86e-3 (18.3e-6)
Left Supramarginal Gyrus	2	3.71	1.16e-3 (11.5e-6)	0.030
			1.15e-3 (12.0e-6)
			1.20e-3 (13.5e-6)
Left Supramarginal Gyrus White Matter	2	4.37	0.82e-3 (8.27e-6)	0.017
			0.81e-3 (7.08e-6)
			0.85e-3 (12.7e-6)
Left Angular Gyrus	2	1.93	1.14e-3 (11.5e-6)	0.153
			1.15e-3 (13.4e-6)
			1.18e-3 (15.5e-6)
Left Angular Gyrus White Matter	2	2.70	0.81e-3 (10.5e-6)	0.075
			0.80e-3 (9.07e-6)
			0.84e-3 (17.7e-6)
Right Superior Parietal Gyrus	2	1.15	1.14e-3 (7.71e-6)	0.322
			1.13e-3 (9.13e-6)
			1.15e-3 (9.83e-6)
Right Superior Parietal Gyrus White Matter	2	2.23	0.82e-3 (14.1e-6)	0.116
			0.79e-3 (7.36e-6)
			0.80e-3 (9.97e-6)
Right Pre-cuneus	2	1.83	1.26e-3 (11.8e-6)	0.169
			1.25e-3 (16.2e-6)
			1.28e-3 (11.9e-6)
Right Pre-cuneus White Matter	2	1.82	0.81e-3 (17.1e-6)	0.170
			0.79e-3 (11.7e-6)
			0.83e-3 (15.2e-6)
Right Supramarginal Gyrus	2	2.44	0.81e-3 (7.48e-6)	0.095
			0.80e-3 (5.91e-6)
			0.83e-3 (11.7e-6)
Right Supramarginal Gyrus White Matter	2	3.05	1.13e-3 (10.8e-6)	0.055
			1.14e-3 (10.3e-6)
			1.16e-3 (11.2e-6)
Right Angular Gyrus	2	5.91	1.14e-3 (13.8e-6)	0.004	0.017 (NC-AD), 0.007 (MCI-AD)
			1.13e-3 (11.5e-6)
			1.20e-3 (15.7e-6)
Right Angular Gyrus White Matter	2	2.67	0.79e-3 (8.72e-6)	0.077
			0.78e-3 (8.34e-6)
			0.81e-3 (14.7e-6)
Left Cingulate Gyrus	2	6.82	1.15e-3 (10.2e-6)	0.002	0.004 (NC-AD), 0.009 (MCI-AD)
			1.14e-3 (13.3e-6)
			1.19e-3 (12.7e-6)
Left Cingulate Gyrus white Matter	2	9.26	0.85e-3 (9.11e-6)	<0.001	0.000 (NC-AD), 0.003 (MCI-AD)
			0.86e-3 (10.3e-6)
			0.92e-3 (13.8e-6)
Right Cingulate Gyrus	2	4.81	1.21e-3 (10.3e-6)	0.011
			1.21e-3 (12.6e-6)
			1.26e-3 (14.4e-6)
Right Cingulate Gyrus White Matter	2	6.80	0.90e-3 (9.73e-6)	0.002	0.009 (NC-AD), 0.004 (MCI-AD)
			0.90e-3 (11.8e-6)
			0.95e-3 (17.4e-6)
Left Cerebellum	2	2.02	1.05e-3 (9.89e-6)	0.141
			1.04e-3 (9.86e-6)
			1.07e-3 (9.25e-6)
Right Cerebellum	2	0.51	1.04e-3 (10.1e-6)	0.604
			1.03e-3 (11.1e-6)
			1.05e-3 (9.34e-6)
Left Pons	2	0.52	0.91e-3 (8.17e-6)	0.597
			0.92e-3 (11.8e-6)
			0.92e-3 (13.4e-6)
Right Pons.	2	0.81	0.96e-3 (7.74e-6)	0.451
			0.97e-3 (13.6e-6)
			0.98e-3 (12.6e-6)