Table 6.
snoRNA | Chromosome | Expression status | Fold change | False discovery rate |
---|---|---|---|---|
PWS versus lean | ||||
ENSG202189 (SNORA30) | 9 | Upregulated | 1.9 | 0.15 |
HBII-85 (SNORD116) (14 separate repeats) | 15 | Downregulated | −22.3 to −1.7 | 3.3 E-10 to 4.4 E-4 |
HBII-438B (SNORD109B) | 15 | Downregulated | −20.0 | 3.3 E-6 |
HBII-438A (SNORD109A) | 15 | Downregulated | −10.0 | 3.6 E-4 |
HBII-436 (SNORD107) | 15 | Downregulated | −1.9 | 0.06 |
PWS versus obese | ||||
ENSG202189 (SNORA30) | 9 | Upregulated | 1.9 | 0.08 |
ENSG239026 (snoU13) | 5 | Upregulated | 1.8 | 0.16 |
HBII-85 (SNORD116) (15 separate repeats) | 15 | Downregulated | −21.9 to −1.7 | 9.8 E-10 to 0.17 |
HBII-438B (SNORD109B) | 15 | Downregulated | −18.0 | 9.2 E-11 |
HBII-438A (SNORD109A) | 15 | Downregulated | −12.1 | 2.1 E-8 |
Notes: No upregulated or downregulated snoRNAs found in obese versus lean. SNORA30 is located in FOCAD and snoU13 is located in DRD1.
Abbreviations: SNORA, small nucleolar RNA (H/ACA Box); SNORD, small nucleolar RNA (C/D Box).