Table 3.
Novel DPIs launched in the last 10 years
| Company | Device | Drug | Description | References |
|---|---|---|---|---|
| 3M | 3M™ Taper | – | A microstructured carrier tape delivers pure drug without carrier excipients | 68 |
| 3M Conix™ | – | Reverse flow cyclone design for particle de-agglomeration | 69 | |
| Almirall Sofotec | Genuair® | Aclidinium | Provides medium airflow resistance and locks-out when empty | 70 |
| Chiesi | NEXThaler® | Beclomethasone and formoterol | DPI releases extra-fine particles with MMAD <2 μm | 71 |
| Cipla | Revolizer | – | Narrow capsule chamber for turbulence and long narrow mouth piece for laminar airflow to reduce oropharyngeal deposition | 72 |
| GSK | Ellipta | Fluticasone furoate | Contains two separate blister strips and requires low inspiratory flow rate | 73 |
| OPKO Medical | Inspiromatic™ | – | Works with extremely low inhalation flow rates and incorporates a micro-pump and vortex to deliver fine particles | 74 |
| Novartis | Breezhaler ® | Indacaterol/glycopyrronium | Offers low resistance to be easily and efficiently used by COPD patients. Patient can check if full dose is inhaled | 75 |
| MannKind | Dreamboat inhaler | Insulin | Simple, small and low cost passive DPI with unit dose cartridges | 76 |
| Disposable Cricket™ Technology | – | Small, low cost device for acute and short treatment durations | 76 | |
| Vectura | Aspirair | – | Mainly for systemic drug delivery through the lungs | 77 |
Abbreviations: DPIs, dry powder inhalers; MMAD, mass median aerodynamic diameter; COPD, chronic obstructive pulmonary disease.